Cannabis and the fibromyalgia syndrome

Fibromyalgia syndrome (FMS) is an enigmatic rheumatic disease. Affected individuals complain of diffuse chronic muscle pain near the joint, but not in the joint itself, and of fatigue, sleep disturbances, depression, and a myriad of other complaints. There are no symptoms that clearly indicate the condition. Therefore, fibromyalgia is often diagnosed with the help of an elaborate process of exclusion. From the time of the first symptoms to the definitive diagnosis, 5-10 years can pass - a period that is often painful and marked by uncertainty for those affected.

There are no figures on the frequency of fibromyalgia. Estimates assume about 0.5% to 5% of the population. In Switzerland one speaks therefore of 40'000 to 400'000 concerning.

Fibromyalgia is still considered incurable. For this reason, scientists and researchers have been working at full speed for some time to find an effective antidote. In the course of this research, the first studies have already been published over the last few years that have examined the treatment of fibromyalgia with cannabinoids such as cannabidiol (CBD) and medical cannabis in greater detail.

Fibromyalgia in science
To date, there is a lack of detailed scientific studies on the effectiveness of CBD in relieving symptoms of fibromyalgia disorder. Below, we present the few promising scientific thrusts to date:

Endocannabinoids: preliminary evidence suggests that endocannabinoids may have a positive impact on the anti-inflammatory process of fibromyalgia patients because they are composed of lipid precursors. Lipids are natural substances found in living organisms that are mainly needed as structural components in cell membranes, as energy stores or as signaling molecules. They then release cannabinoid receptors with the help of neurotransmitters or immune cells, enabling them to activate neighboring cells and exert their anti-inflammatory effect.

Lipo-amino acids: Lipo-amino acids, an endogenous subfamily of eicosanoids, are structurally and metabolically related to endocannabinoids and exhibit similar anti-inflammatory and analgesic properties. However, their efficacy in relation to fibromyalgic symptoms has yet to be studied in depth scientifically.

Link to studies:

The information and data that served as the basis for the preparation of this article were taken from professional articles, trade journals or studies. Medropharm is not authorized to make any healing and/or efficacy promises related to their cannabis products.

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